DNA methylation is very important for normal development and has been involved in many pathologies including cancer. Our knowledge of the distribution of the DNA methylation genome, how it changes… Read more »
Corticosteroids, ionoffor calcium and anti-CD3 monoclonal antibodies kill simoocyte mice incubated in vitro. Cell death is preceded by extensive DNA fragmentation into the oligonucleosomom subunit. This type of death (apoptosis),… Read more »
Insulin resistance arises from insulinability to act normally in regulating nutritional metabolism on peripheral networks. The increasing evidence of the study of human population and animal research has established correlative… Read more »
Endotoxin, gram-negative bacterial constituents, stimulates macrophages to release a large number of tumor necrosis (TNF) and interleukin-1 (IL-1) factors (IL-1), which can trigger tissue injury and deadly surprises (endotoxemia). TNF… Read more »
The apoptosis and autophagy both regulate the biological processes that play a central role in network homeostasis, development, and disease. Anti-apoptotic protein, BCL-2, interact with evolutionary autophagy protein, beclin 1…. Read more »
Differentiated cells can be reprogrammed to a state such as embryonic by transferring nuclear content to oocytes or with fusion with embryonic stem cells. Little is known about the factors… Read more »
