Antipoptotic protein BCL-2 inhibits autophagy 1-dependent.

Antipoptotic protein BCL-2 inhibits autophagy 1-dependent.

The apoptosis and autophagy both regulate the biological processes that play a central role in network homeostasis, development, and disease. Anti-apoptotic protein, BCL-2, interact with evolutionary autophagy protein, beclin 1. However, a little known about the functional significance of this interaction. Here, we indicate that the antipoptotic protein BCL-2 wild type, but not binding 1 mutant that is damaged from BCL-2, inhibits autophagy 1-dependent in yeast and mammals and that BCL-2-transgenic expression of BCL-2 inhibits autophagy in the heart of the muscle.

Furthermore, Becklin 1 mutant that cannot bind BCL-2 pushes more autophagy than the type of wild Beck 1 and, unlike the type of wild Becker 1, promotes cell death. Thus, BCL-2 not only functions as an antipoptotic protein, but also as an antiautophagy protein through its inhibitory interaction with Becklin 1. This antiautophagy function of BCL-2 can help keep autophagy at a level compatible with cell survival, not death cells.

Identify the specific microrna network from the mouse.

Microrna (MIRNAS) is a new class of RNA not coded, which is encoded as a short reverse repetition in the invertebrate genome and vertebrate. It is believed that MIRNAS is a translation modulator and stability of the target MRNA, although most MRNAS targets remain identified. Here we describe identifying 34 mirnas novels with network-specific cloning around 21-nucleotides RNA from the mouse. Almost all MIRNAs identified are preserved in the human genome and are also often found in nonmamalia vertebrate genomes, such as pufferfish.

In the heart, heart, or brain, it was found that the Mirna expressed specifically the network dominated the MIRNA population expressed and showed the role for MIRNAs in network specifications or cell lineage decisions. Finally, Mirna was identified that seemed to be a fruit orthologist and Mammal C. Elegans Lin-4 Strna.

Micronas modulates the differentiation of hematopoietic lines.

Microrna (MIRNAS) is an abundant class of RNAS 22-nucleotide regulation found in plants and animals. Some MIRNAS plants, Elegans Caenorhabditis, and Drosophila played the role of important gene regulations during development with paired to target Mr.NNAS to determine posttransciptional repression from these messages. We identified three MIRNAs specifically expressed in hematopoietic cells and showed that their expressions were regulated dynamically during early hematopoiesis and commitment of lineage. One of the MIRNAs, MIR-181, especially stated in B-lymphoidal cells from the mouse bone marrow, and its ectopic expression in hematopoietic stem cells causes increased B cell-line cell fraction in both network culture differentiation tests. and adult mice. Our results indicate that Microrna is a component of the molecular circuit that controls the hematopoiesis mouse and suggests that other microrna has a similar regulatory role during other aspects of vertebrate developments.

Dystrophin: Protein products from Locus Dystrophy Muscle Duchenne.

Protein products from Dychenne Duchenne Locus Dystrophy (DMD) and homologous mouse (MDMD) have been identified using polyclonal antibodies directed towards fusion proteins containing two different regions of MDMD CDNA. DMD proteins are proven to be around 400 KD and to represent around 0.002% of the total lurik muscle protein. This protein is also detected in plain muscle (stomach).

Muscle tissue isolated from both boys affected by DMD and MDX mice do not contain DMD proteins detected, indicating that this genetic disorder is homologous. Because MDX mice present there are no clear clinical abnormalities, the identification of the MDX corpse as an animal model for DMD has important implications in connection with the deadly etiology of DMD phenotypes. We have named the dytrophin protein because of identification through the insulation of Duchenne muscle locus dystrophy.

Antipoptotic protein BCL-2 inhibits autophagy 1-dependent.

Blood monocy consists of two main subsets with different migration properties.

Peripheral blood monocytes are heterogeneous leukocyte populations circulating. Using the Murine Adoption Transfer System to investigate Homing and Monocyte Differentiation in Vivo, we identify two functional parts of the Murine Blood Monocytes: CCR2 (LO) CR1 (+) which is short-lived (+) which is actively recruited for inflamed tissue and CCR (3) (hi) CCR1 (-) (-) subset (-) which is marked with CX (3) recruitment that depends on the CR1 on noninflamed networks. Both subsets have the potential to distinguish dendritic cells in in vivo.

Human MYC Associated Factor X (MAX) ELISA Kit

DLR-MAX-Hu-48T 48T
EUR 517
Description: A sandwich quantitative ELISA assay kit for detection of Human MYC Associated Factor X (MAX) in samples from tissue homogenates or other biological fluids.

Human MYC Associated Factor X (MAX) ELISA Kit

DLR-MAX-Hu-96T 96T
EUR 673
Description: A sandwich quantitative ELISA assay kit for detection of Human MYC Associated Factor X (MAX) in samples from tissue homogenates or other biological fluids.

Human MYC Associated Factor X (MAX) ELISA Kit

RDR-MAX-Hu-48Tests 48 Tests
EUR 544

Human MYC Associated Factor X (MAX) ELISA Kit

RDR-MAX-Hu-96Tests 96 Tests
EUR 756

Po (P-Zero)

CH23009 100 ul
EUR 179

T1 Simple Cloning Kit

20-abx098056
  • EUR 495.00
  • EUR 662.00
  • 20 rxns
  • 60 rxns

Blunt Simple Cloning Kit

20-abx098060
  • EUR 495.00
  • EUR 662.00
  • 20 rxns
  • 60 rxns

pUC57 Simple-PVT1 Plasmid

PVTB00511 2 ug
EUR 356

pUC57 Simple-Pdcd4 Plasmid

PVTB70003 2 ug
EUR 356

pUC57- Simple- gRNA backbone

PVT11371 2 ug
EUR 301

Protein Max (MAX) Antibody

abx117235-100ug 100 ug
EUR 467

Protein Max (MAX) Antibody

20-abx123505
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Protein Max (MAX) Antibody

20-abx312892
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protein Max (MAX) Antibody

20-abx001769
  • EUR 411.00
  • EUR 592.00
  • EUR 182.00
  • EUR 314.00
  • 100 ul
  • 200 ul
  • 20 ul
  • 50 ul

Protein Max (Max) Antibody

abx146651-100ug 100 ug
EUR 439

Protein Max (MAX) Antibody

abx431420-200ul 200 ul
EUR 384

Protein Max (MAX) Protein

20-abx260587
  • EUR 2861.00
  • EUR 328.00
  • EUR 230.00
  • 1 mg
  • 25 ug
  • 5 ug

Protein Max (MAX) Antibody

abx235033-100ug 100 ug
EUR 481

Giemsa stain

GB0477 10g
EUR 60.44

Jenner's Stain

GT5545-100G 100 g
EUR 160

Jenner's Stain

GT5545-25G 25 g
EUR 81

Giemsa Stain

GT6821-100ML 100 ml
EUR 46

Giemsa Stain

GT6821-250ML 250 ml
EUR 59

Wright's stain

GT7819-100G 100 g
EUR 110

Wright's stain

GT7819-10G 10 g
EUR 46

Wright's stain

GT7819-250G 250 g
EUR 190

Wright's stain

GT7819-25G 25 g
EUR 58

Giemsa stain

20-abx082069
  • EUR 175.00
  • EUR 217.00
  • 1 g
  • 5 g

Giemsa stain

20-abx082518
  • EUR 175.00
  • EUR 217.00
  • 1 g
  • 5 g

DiI Stain

B2742-250 250 mg
EUR 753

DiI Stain

B2742-50 50 mg
EUR 227

Fmoc-Ser(PO(OBzl)OH)-OH

B-3455.0001 1.0g
EUR 297
Description: Sum Formula: C25H24NO8P; CAS# [158171-14-3]

Fmoc-Ser(PO(OBzl)OH)-OH

B-3455.0005 5.0g
EUR 1093
Description: Sum Formula: C25H24NO8P; CAS# [158171-14-3]

Fmoc-Thr(PO(OBzl)OH)-OH

B-3460.0001 1.0g
EUR 321
Description: Sum Formula: C26H26NO8P; CAS# [175291-56-2]

Fmoc-Thr(PO(OBzl)OH)-OH

B-3460.0005 5.0g
EUR 1192
Description: Sum Formula: C26H26NO8P; CAS# [175291-56-2]

Fmoc-Tyr(PO(OBzl)OH)-OH

B-3565.0001 1.0g
EUR 345
Description: Sum Formula: C31H28NO8P; CAS# [191348-16-0]

Fmoc-Tyr(PO(OBzl)OH)-OH

B-3565.0005 5.0g
EUR 1288
Description: Sum Formula: C31H28NO8P; CAS# [191348-16-0]

Fish phenol oxidase (PO) ELISA Kit

QY-E160047 96T
EUR 478

Protein Max (MAX) Antibody (HRP)

20-abx312893
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protein Max (MAX) Antibody (FITC)

20-abx312894
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protein Max (MAX) Antibody (Biotin)

20-abx312895
  • EUR 411.00
  • EUR 1845.00
  • EUR 599.00
  • EUR 182.00
  • EUR 300.00
  • 100 ug
  • 1 mg
  • 200 ug
  • 20 ug
  • 50 ug

Protein Stain-EZ C, Reversible Copper Stain Kit

BSP017 1kit, 10prep
EUR 74.36

Protein Stain-EZ B, Reversible Zinc Stain Kit

BSP019 1kit, 10prep
EUR 74.36

Protein Stain-EZG Rapid Coomassie Blue Stain Solution

BSP041 1KIT, 10prep
EUR 76.1

4CN Stain Kit

PW024 5Preps, 5prep
EUR 70.88

TMB Stain Kit

PW025 5Preps, 5prep
EUR 70.88

Jenner's Stain, certified

GT1148-25G 25 g
EUR 107

Giemsa stain, powder

GT7801-100G 100 g
EUR 134

Giemsa stain, powder

GT7801-10G 10 g
EUR 46

Giemsa stain, powder

GT7801-25G 25 g
EUR 62

Giemsa stain, powder

GT7801-50G 50 g
EUR 86

Giemsa stain, powder

GT7801-5G 5 g
EUR 42

ClearSight DNA Stain

BH40501 1ml
EUR 103
Description: For DNA staining and vizualization.

ClearSight RNA Stain

BH40601 400µl
EUR 77
Description: For DNA staining and vizualization.

Silver Stain kit

AR0171 1 kit (for 30 assays to stain the gel of 5 X8.5)
EUR 152

Fite's Stain Kit

FLS-1 125 ml ea.
EUR 149

Fite's Stain Kit

FLS-500 500 ml ea.
EUR 295

Trichrome Stain (Blue)

TGB125 125 ml
EUR 74

Trichrome Stain (Blue)

TGB500 500 ml
EUR 116

Trichrome Stain (Blue)

TGB999 1000 ml
EUR 143

Pneumocystis Stain Kit

PCS-1 1 kit(s)
EUR 156

Pneumocystis Stain Kit

PCS-2 100 Slides
EUR 104

Reticulum Stain Kit

GRT-1 1 kit(s)
EUR 255

Reticulum Stain Kit

GRT-2 1 kit(s)
EUR 152

Gram Stain Kit

GSK-1 125 ml ea.
EUR 125

Gram Stain Kit

GSK-2 30 ml ea.
EUR 92

Gram Stain Kit

GSK-500 500 ml ea.
EUR 303

Iron Stain Kit

IRN-1 1 kit(s)
EUR 149

Iron Stain Kit

IRN-2 100 Slides
EUR 101

GMS Stain Kit

KAA-1 125 ml ea.
EUR 216

GMS Stain Kit

KAA-1000 1000 ml ea.
EUR 884

GMS Stain Kit

KAA-500 500 ml ea.
EUR 523

Copper Stain Kit

CSK-1 1 kit(s)
EUR 189

Copper Stain Kit

CSK-2 1 kit(s)
EUR 120

Fite's Stain Kit

K1425-125
EUR 370

Geimsa Stain Kit

K1426-30
EUR 289

Geimsa Stain Kit

K1426-500
EUR 468

GMS Stain Kit

K1427-125
EUR 446

Gram Stain Kit

k1428-125
EUR 392

Gram Stain Kit

k1428-30
EUR 262

Orcein Stain Kit

K1432-125
EUR 501

Orcein Stain Kit

K1432-30
EUR 359

Pneumocystis Stain Kit

K1434-125
EUR 425

Pneumocystis Stain Kit

K1434-30
EUR 316

Steiner Stain Kit

K1435-125
EUR 446

Papanicolaou Stain Kit

K1440-30
EUR 207

Papanicolaou Stain Kit

K1440-500
EUR 278

Human MAX/ Protein max ELISA Kit

E1557Hu 1 Kit
EUR 571

Chicken Protein max (MAX) ELISA Kit

abx512851-96tests 96 tests
EUR 911

Mouse Protein max (MAX) ELISA Kit

abx512853-96tests 96 tests
EUR 668

Rat Protein max (MAX) ELISA Kit

abx512854-96tests 96 tests
EUR 668

Human Protein max (MAX) ELISA Kit

abx253842-96tests 96 tests
EUR 668

Human MAX(Protein max) ELISA Kit

EH0886 96T
EUR 567.6
Description: Method of detection: Double Antibody, Sandwich ELISA;Reacts with: Homo sapiens;Sensitivity: 0.094 ng/ml

MAX Antibody

1-CSB-PA010072
  • EUR 222.00
  • EUR 195.00
  • 100ug
  • 50ug
Description: A polyclonal antibody against MAX. Recognizes MAX from Human, Mouse, Rat. This antibody is Unconjugated. Tested in the following application: IHC, ELISA;IHC:1/100-1/300.ELISA:1/10000

The level of expression of CX (3) CR1 also defines two main human monocyte sets, CD14 (+) CD16 (-) and CD14 (LO) monocytes, which share the potential for phenotypes and homing with the mouse set. These findings raise the potential of new therapeutic strategies in inflammatory diseases.

 

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